by Barry Keate
Ginkgo biloba extract has been clinically proven in numerous studies to reduce tinnitus and continues to play a critical role in relief from ringing in the ears. Arches takes pride in having consistently used the highest quality ginkgo found on the world market. This dedication to quality continues to produce excellent results for the majority of our customers with tinnitus.
Over the last two years we have improved upon the standardized extract by increasing the concentration and potency of the individual components. Our ginkgo is now considered so unique to have been awarded US Trademark protection under the name Ginkgo Max 26/7®.
I will explain below just why our 26/7 extract is so important for your tinnitus versus the industry standard 24/6 ginkgo.
After years of research and using newly developed extraction technologies, we have developed a customized extract that is specifically designed for people who suffer from tinnitus. This is the first ginkgo formulation in the world created expressly for tinnitus.
For those currently using Arches Tinnitus Formula, please know we have been using this same new extract since 2013. We have only now received trademark protection, have developed a new logo and bottle label, and are formally introducing the trademarked product.
What is Ginkgo Biloba?
Ginkgo biloba extract comes from the leaves of the Ginkgo biloba tree, one of the oldest living tree species in the world. The Dr. Willmar Schwabe Company of Germany, a large pharmaceutical company, developed and defined the first extract, which was known as EGb 761.
The German Commission E is similar to the Food and Drug Administration in the US. It regulates the manufacture and sale of all herbal supplements in Germany. According to the Commission E, Ginkgo biloba extract EGb 761 must contain a minimum of 24% flavonol glycosides and 6% terpene lactones. Additionally, individual components in these categories are required to have minimal amounts specified. The terpene lactones contain Ginkgolides A, B and C which are required to amount to 2.8%, and bilobalide, which is required to contain a minimum of 2.6%. Ginkgolic acid, which is an allergen and an undesirable component, is to be kept below 5 ppm (parts per million).
This extract has become known in the US as Ginkgo biloba 24/6 after the amounts of flavonol glycosides and terpene lactones that are found in it.
EGb 761 has become the most studied herbal extract in the world. More than 400 clinical studies have been conducted on this extract and have shown positive results for many health concerns including: glaucoma, cerebral insufficiency, intermittent claudication (pain while walking), depression, dizziness, headache, Alzheimer’s disease, and tinnitus, among many others.
Ginkgo Biloba Extract for Tinnitus
Before we go into why our new formulation is better for tinnitus, it is necessary to understand how it works and the mechanisms of action in reducing tinnitus symptoms. There are three primary mechanisms by which ginkgo is helpful for tinnitus.
1 – Increased circulation. The terpene lactones increase blood circulation, especially in the microcapillaries that feed the brain, ears and eyes. They do this by acting as a vasodilator, relaxing the blood vessels, and by inhibiting Platelet Activating Factor (PAF), which causes blood platelets to lump together, slowing circulation.
By increasing circulation within the inner ear, ginkgo promotes the uptake of glucose and oxygen (nutrients in the inner ear), and allows built-up toxins to be flushed away, speeding the healing process.
2 – Antioxidant properties. Free radical molecules are those produced during certain disease and distress states and cause untold damage to tissues and neuronal structures. Free radicals are produced when noise exposure or other trauma affects the inner ear. These can damage or destroy neuroreceptors in the auditory pathway. The flavone glycosides in ginkgo are powerful antioxidants that help prevent free radical damage.
3 – Glutamate antagonism and neuroprotection. This is one of the primary ways Ginkgo biloba can help reduce the effects of tinnitus. Glutamate is an excitatory neurotransmitter in the inner ear and auditory pathway. When damage is done to the hair cells in the cochlea, glutamate floods the entire auditory pathway. Too much glutamate excites the neuroreceptors in the inner ear and causes them to fire chemical bursts until they become depleted and die.
Bilobalide, one of the terpene lactones, is a potent antagonist to glutamate release. It also keeps GABA, the calming neurotransmitter, active in the system, which counterbalances the effects of glutamate. Bilobalide is a powerful neuroprotector and is potently therapeutic in many cerebrovascular and neurodegenerative disorders such as tinnitus.
These properties of Ginkgo biloba are discussed in more detail in our article, Arches Tinnitus Formula: The Science Behind The Product.
ConsumerLab.com and Ginkgo
It is important to know that most Ginkgo biloba products in the US are not what they purport to be. ConsumerLab.com has conducted independent testing of a large number of over-the-counter products and found more than 77% of these products “lacked adequate levels of one or more important compounds expected of clinically effective ginkgo.”
Of particular importance is that 67% of these products contained less than 20% of the specified amount of bilobalide. This means that the great majority of retail ginkgo products in the US contain less than 0.5% bilobalide (20% of the required 2.6%). This is the compound most important for the reduction of glutamate toxicity and neuroprotection! This is one reason why many over-the-counter brands of ginkgo are ineffective against tinnitus.
Ginkgo Max 26/7® – The Most Effective Ginkgo Biloba… Ever
Arches has used the understanding of how ginkgo helps reduce tinnitus to create a new, more powerful extract designed specifically for people with tinnitus. We have done this by using more raw material and refining it further to produce a more potent composition. This is considerably more expensive than using a lower potency product but is also much more effective for tinnitus.
We have increased the flavonol glycoside component from the standard 24% to a minimum of 26%. The terpene lactone content has increased from 6% to a minimum of 7%. Ginkgolides A, B and C have increased from 2.8% to a minimum of 4%.
Perhaps most importantly, the bilobalide content in our extract has increased from 2.6% (or 0.5% in most products) to a minimum of 3.6%, a 40% increase over standardized 24/6 Ginkgo extract. Simultaneously the ginkgolic acid has been reduced to less than 0.5 ppm.
Components Standard 24/6 Extract Ginkgo Max 26/7 (min)
Flavonol Glycosides 24% 26%
Terpene Lactones 6% 7%
Ginkgolides A, B and C 2.8% 4%
Bilobalide 2.6% 3.6%
It is also important to know that our formulation guarantees that these are minimum requirements and in most cases the components are present in higher amounts. The Certificate of Analysis for Ginkgo Max 26/7 shows the absolute analysis with flavonol glycosides at 26.7%, terpene lactones at 8.16% and bilobalide at 3.68%. This is a huge improvement over the old standardized product.
Ginkgo Max 26/7® represents a major breakthrough in ginkgo extraction and improved efficacy. It is my sincere hope and belief that this formulation will be helpful to an even greater number of people, helping to further improve the lives of those who live every day with tinnitus.