The Importance of B-12
with Methyl-Cobalamin for Tinnitus

New and Improved!

Arches Tinnitus B-12 Formula™
now uses better absorbing Methylcobalamin

Studies show many people with tinnitus
have a B12 defeciency.

Methylcobalamin is a type of Vitamin B12. Vitamin B12 comes in several kinds including hydroxy-, cyano-, and adenosyl-cobalamin, but only the methyl form is used in the central nervous system. Deficiency states are fairly common and vitamin B12 deficiency mimics many other disease states of a neurological or psychological kind, and it causes anemia. Cyanocobalamin (the kind in most vitamin supplements) is converted by the liver into methylcobalamin but not in therapeutically significant amounts.

WHAT DOES METHYL B12 DO?

Methylcobalamin has been shown to protect against glutamate-induced excitotoxic neuronal damage. Neuronal damage caused by excess glutamate is one of the primary causes of tinnitus and worsens existing tinnitus.

Methylcobalamin is immediately active upon absorption while other forms (e.g. cyanocobalamin) need to be converted first into methylcobalamin in a two step process.Methylcobalamin donates methyl groups to the myelin sheath that insulates nerve fibers and regenerates damaged neurons. In a B12 deficiency, toxic fatty acids destroy the myelin sheath but high enough doses of B12 can repair it.

Clinical Study on B-12 and Tinnitus
A important study by Shemesh et al. (1993) showed a high prevalence (47%) of vitamin B-12 deficiency in patients with chronic tinnitus. This deficiency was more widespread and severe in the tinnitus group that was associated with noise exposure. Supplemental cobalamin was found to provide some relief in several patients with severe tinnitus.

This suggests a relationship between vitamin B-12 deficiency and dysfunction of the auditory pathway. Supplemental B-12 was found to provide some relief in several patients with severe tinnitus.

A Taste of Raspberry
Because B-12 is poorly absorbed when ingested, a suggested daily dose is 1000 mcg. Vitamin B-12 is better absorbed if it is dissolved under the tongue. Arches Tinnitus B-12 Formula™ is a mild raspberry flavored sublingual that absorbs directly to the blood stream.

Dr. Michael Seidman on B Vitamins:

"Most B-complex vitamins cannot be stored in the body and must be replaced daily from food sources or supplements. B vitamins help maintain healthy skin, eyes, muscle tone and support the functions of the liver and central nervous system. They are also extremely important in helping to deal with depression, stress and anxiety. The variety of B vitamins are normally taken together but occasionally one B vitamin is used to treat a particular disorder. Deficiency in B vitamins can result in weakness, low blood counts, skin and hair problems, nervousness, poor night vision, tinnitus and hearing loss.Vitamin B-complex supplements appear to be effective in some patients with tinnitus by providing a stabilizing effect on the nerves."
                                       Michael Seidman, M.D., F.A.C.S