Alcoholism Drug to be Studied for Treatment of Tinnitus
Oregon Health & Science University (OSHU), Oregon state’s only health and research university has received funding to conduct a study on a medication previously used for the treatment of alcoholism to see if it may be effective in reducing symptoms of tinnitus.
There has been previous evidence that suggests the drug, Acamprosate, used to treat alcoholism may indeed be viable for tinnitus. A small clinical trial in Brazil conducted on 25 tinnitus patients in Brazil showed that 87% had some degree of relief and nearly 48% had a reduction of more than 50%. 1
The study had the shortcoming of having a small number of participants and researchers speculated that those on the active medication were aware of it due to the marked drowsiness associated with the drug. They also say the drowsiness itself may have contributed to improvement as many tinnitus patients have trouble sleeping. The OSHU study plans on having over 150 participants.
Billy Martin, Ph.D., professor of otolaryngology/head and neck surgery, and director of the OHSU Tinnitus Clinic believes that since Acamprosate can restore balance between two competing neurotransmitters in the brain, it may also serve the same role in tinnitus suffers.
Neurotransmitters in the brain conduct information between brain cells. An imbalance of neurotransmitters occurs in alcoholics and scientists speculate that those suffering with ringing in the ears may have the same type of imbalance
Researchers hope to identify, by the close of the study, the common characteristics of people who respond to the medication, for example tinnitus pitch, degree of sleep problems and level of hearing loss.
We spoke with OSHU project coordinator Linda Howarth, who told us the study is now open for participants to apply. Each individual must first answer a series of questions to see if they qualify for participation. 150+ qualified individuals will be accepted to participate. Inquiries should be directed to Linda Howarth at (503) 494-0670.
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Rev Bras Otorrinolaringol (Engl Ed). 2005 Sep-Oct; 71(5):618-23. Epub 2006 Mar 31. Tinnitus treatment with acamprosate: double-blind study. Azevedo AA, Figueiredo RR.
Brent Curtis – Editor
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Oregon Health & Science University (OSHU), Oregon state’s only health and research university has received funding to conduct a study on a medication previously used for the treatment of alcoholism to see if it may be effective in reducing symptoms of tinnitus.
There has been previous evidence that suggests the drug, Acamprosate, used to treat alcoholism may indeed be viable for tinnitus. A small clinical trial in Brazil conducted on 25 tinnitus patients in Brazil showed that 87% had some degree of relief and nearly 48% had a reduction of more than 50%. 1
The study had the shortcoming of having a small number of participants and researchers speculated that those on the active medication were aware of it due to the marked drowsiness associated with the drug. They also say the drowsiness itself may have contributed to improvement as many tinnitus patients have trouble sleeping. The OSHU study plans on having over 150 participants.
Billy Martin, Ph.D., professor of otolaryngology/head and neck surgery, and director of the OHSU Tinnitus Clinic believes that since Acamprosate can restore balance between two competing neurotransmitters in the brain, it may also serve the same role in tinnitus suffers.
Neurotransmitters in the brain conduct information between brain cells. An imbalance of neurotransmitters occurs in alcoholics and scientists speculate that those suffering with ringing in the ears may have the same type of imbalance
Researchers hope to identify, by the close of the study, the common characteristics of people who respond to the medication, for example tinnitus pitch, degree of sleep problems and level of hearing loss.
We spoke with OSHU project coordinator Linda Howarth, who told us the study is now open for participants to apply. Each individual must first answer a series of questions to see if they qualify for participation. 150+ qualified individuals will be accepted to participate. Inquiries should be directed to Linda Howarth at (503) 494-0670.
-
Rev Bras Otorrinolaringol (Engl Ed). 2005 Sep-Oct; 71(5):618-23. Epub 2006 Mar 31. Tinnitus treatment with acamprosate: double-blind study. Azevedo AA, Figueiredo RR.
Brent Curtis – Editor
Book Mark it-> del.icio.us | Reddit | Slashdot | Digg | Facebook | Technorati | Google | StumbleUpon | Window Live | Tailrank | Furl | Netscape | Yahoo | BlinkList
